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Background.

Blood and marrow transplantation (BMT) is playing an increasing role in the management of patients with otherwise fatal diseases of the hematopoietic and immune system and solid tumours. Currently, over 1200 transplants are performed annually by 23 Canadian programs, with the number of transplants and transplant centres growing every year. New technologies and management strategies for improving the success of BMT are emerging rapidly from academic centres and industry; their expeditious testing, timely dissemination of results and subsequent implementation are mandatory to ensure the best care and risk management for Canadians in need of a transplant.

While Canada's healthcare system offers a uniquely favourable environment for testing new therapies, relatively few large and decisive Canadian trials have been completed. While large-scale studies demand resources and patient participants very often beyond that which is available in a single Canadian centre, a network of cooperating centres would allow Canadians to conduct large and decisive studies in a timely manner. To this end, the CBMTG has established the Clinical Trials Network (CBMTG-CTN).


Mission.

The mission of the CBMTG-CTN is:

  • to improve the safety, availability, and efficacy of hematopoietic stem cell transplantation for adults and children in Canada;
  • to perform clinical research trials that will define optimal hematopoietic stem cell transplantation for adults and children;
  • to conduct laboratory research that will translate into more effective treatments with reduced short and long-term side effects;
  • to build partnerships that will help fulfill the mission of the Canadian Blood and Marrow Transplant Group and improve the health of adults and children throughout the world.


Activities.

Chaired by Dr. Ronan Foley, the CBMTG Clinical Trials Network Committee (CTNC) governs the overall activities of the Clinical Trials Network (CTN), including reviewing and approving the research agenda, formulating and monitoring policies and procedures, guiding research activities and overseeing communications within the CTN and with the greater scientific community and public. Research concept proposals are solicited, developed and managed by Subcommittees of the CTNC.

More information is available to members of the CBMTG. Click here to find out more.